Fimbriae reprogram host gene expression – Divergent effects of P and type 1 fimbriae
نویسندگان
چکیده
منابع مشابه
Evolutionary Analysis Points to Divergent Physiological Roles of Type 1 Fimbriae in Salmonella and Escherichia coli
UNLABELLED Salmonella and Escherichia coli mannose-binding type 1 fimbriae exhibit highly similar receptor specificities, morphologies, and mechanisms of assembly but are nonorthologous in nature, i.e., not closely related evolutionarily. Their operons differ in chromosomal location, gene arrangement, and regulatory components. In the current study, we performed a comparative genetic and struct...
متن کاملExpression of P fimbriae of uropathogenic Escherichia coli strains.
The occurrence of P fimbriae in a total of 222 uropathogenic Escherichia coli (UPEC) strains was investigated. Out of the total, 31 (14%) were P fimbriated. Of 24 pyelonephritogenic E. coli strains, three (13%) with P fimbriae occurred in children with clinical pyelonephritis, and of 198 E. coli strains 29 (15%) occurred in children with cystitis. Prevalence of P fimbriae of E. coli strains was...
متن کاملP-fimbriae, bacterial adhesion, and pyelonephritis.
Everyday observations usually seem self evident and are often not given the attention they merit. Examples are the fact that I haemolytic streptococci cause sore throat but not pneumonia; gonococci cause urethritis but not urinary tract infection (UTI) (which Escherichia coli do); and bacteria like Neisseria gonorrhoea and Bordetella pertussis that cause human disease are often harmless in anim...
متن کاملP - fimbriae , bacterial adhesion , and pyelonephritis JAN
Everyday observations usually seem self evident and are often not given the attention they merit. Examples are the fact that I haemolytic streptococci cause sore throat but not pneumonia; gonococci cause urethritis but not urinary tract infection (UTI) (which Escherichia coli do); and bacteria like Neisseria gonorrhoea and Bordetella pertussis that cause human disease are often harmless in anim...
متن کاملModeling fimbriae mediated parasite-host interactions.
Type 1 fimbriae are a known virulence factor in a number of pathogenic enterobacteriaceae, including Salmonella, Shigella and E. coli. Yet, they are also expressed by some commensal strains, notably of E. coli. One hypothesis of the role of fimbriae in commensals is that they evoke a small but tolerable host immune response in order to have the host release sialic acid, which is a valuable nutr...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2019
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1007671